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  • Food-Related Stories
    Food-Related Stories

    “Gaby Melian tells so many stories through her relationship with food—about love, about loss, about hard work, and about finding her passion.The pages are dripping with delicious smells and tastes, and will give you a new way to look at both cooking and what it means to have a plan.” —Molly Birnbaum, editor in chief, America’s Test Kitchen KidsIn this moving, personal account, chef and activist Gaby Melian shares her journey with food and how creating a relationship with food -- however simple or complicated -- is a form of activism in its own right. Pocket Change Collective was born out of a need for space.Space to think. Space to connect. Space to be yourself. And this is your invitation to join us. This is a series of small books with big ideas from today's leading activists and artists. "Food rescued me so many other times -- not only because I sold food to survive.I cook to entertain; I cook to be liked; I cook to be loved." In this installment, chef and activist Gaby Melian shares her personal journey with food -- from growing up in Argentina to her time as a Jersey City street vendor and later, as Bon Appetit's test kitchen manager.Powerful and full of heart, here, Melian explores how we can develop a relationship with food that's healthy, sustainable, and thoughtful.

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  • SCN2A-Related Disorders
    SCN2A-Related Disorders

    SCN2A encodes a voltage-gated sodium channel (designated NaV1.2) vital for generating neuronal action potentials.Pathogenic SCN2A variants are associated with a diverse array of neurodevelopmental disorders featuring neonatal or infantile onset epilepsy, developmental delay, autism, intellectual disability and movement disorders.SCN2A is a high confidence risk gene for autism spectrum disorder and a commonly discovered cause of neonatal onset epilepsy.This remarkable clinical heterogeneity is mirrored by extensive allelic heterogeneity and complex genotype-phenotype relationships partially explained by divergent functional consequences of pathogenic variants.Emerging therapeutic strategies targeted to specific patterns of NaV1.2 dysfunction offer hope to improving the lives of individuals affected by SCN2A-related disorders.This Element provides a review of the clinical features, genetic basis, pathophysiology, pharmacology and treatment of these genetic conditions authored by leading experts in the field and accompanied by perspectives shared by affected families. This title is also available as Open Access on Cambridge Core.

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  • SCN2A-Related Disorders
    SCN2A-Related Disorders

    SCN2A encodes a voltage-gated sodium channel (designated NaV1.2) vital for generating neuronal action potentials.Pathogenic SCN2A variants are associated with a diverse array of neurodevelopmental disorders featuring neonatal or infantile onset epilepsy, developmental delay, autism, intellectual disability and movement disorders.SCN2A is a high confidence risk gene for autism spectrum disorder and a commonly discovered cause of neonatal onset epilepsy.This remarkable clinical heterogeneity is mirrored by extensive allelic heterogeneity and complex genotype-phenotype relationships partially explained by divergent functional consequences of pathogenic variants.Emerging therapeutic strategies targeted to specific patterns of NaV1.2 dysfunction offer hope to improving the lives of individuals affected by SCN2A-related disorders.This Element provides a review of the clinical features, genetic basis, pathophysiology, pharmacology and treatment of these genetic conditions authored by leading experts in the field and accompanied by perspectives shared by affected families. This title is also available as Open Access on Cambridge Core.

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  • Oncology Treatment-Related Cardiotoxicity
    Oncology Treatment-Related Cardiotoxicity


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  • How are inflation, the corona pandemic, and the war in Ukraine related?

    Inflation, the corona pandemic, and the war in Ukraine are related in several ways. The corona pandemic has disrupted global supply chains, leading to shortages of goods and higher production costs, which has contributed to inflationary pressures. The war in Ukraine has also disrupted global supply chains, particularly for commodities such as energy and agricultural products, further contributing to inflation. Additionally, the geopolitical tensions and uncertainty caused by the war in Ukraine have also contributed to market volatility and increased inflation expectations. Overall, these factors have created a complex and interconnected global economic environment that has impacted inflation dynamics.

  • What are good essay topics related to England?

    Some good essay topics related to England could include the impact of the Industrial Revolution on English society, the role of the British monarchy in modern times, the influence of English literature on the world, the history and significance of Stonehenge, and the impact of Brexit on the UK and Europe. Additionally, you could explore the cultural significance of English traditions such as afternoon tea, the history of English colonization and its impact on the world, or the evolution of the English language.

  • What are some good car-related YouTube channels?

    Some good car-related YouTube channels include Doug DeMuro, who provides in-depth reviews and quirky features on a wide range of vehicles. For those interested in automotive engineering and technology, Engineering Explained offers detailed explanations of how cars work and the science behind various automotive systems. If you're into car modifications and tuning, Mighty Car Mods is a fun channel that showcases DIY projects and performance upgrades on a variety of cars. Finally, for those who enjoy classic cars and restoration projects, Hagerty is a great channel that features vintage car reviews, restoration tips, and historical automotive content.

  • What are the most well-known positive and negative utopias related to philosophy?

    One of the most well-known positive utopias related to philosophy is Plato's "Republic," which envisions an ideal society governed by philosopher-kings and based on justice and virtue. On the other hand, one of the most well-known negative utopias is George Orwell's "1984," which depicts a totalitarian society where individual freedoms are suppressed and government control is absolute. Both of these works have had a significant impact on philosophical discussions about the nature of society and the role of government.

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  • Age-Related Macular Degeneration
    Age-Related Macular Degeneration

    The value of Age-Related Macular Degeneration has stood the test of time, but progress in both basic and clinical ophthalmology has been relentless, mandating the need for an updated book.This second edition focuses on the pathophysiology and the epidemiology of age-related macular degeneration (AMD), the clinical features and management of dry and wet AMD, imaging techniques, and medical therapy for both non-neovascular AMD and neovascular AMD.It describes both clinically validated and experimental therapies as well as rehabilitation technology, and presents strategies to prevent the progression of non-exudative AMD.Results from current clinical trials are also included. New chapters in this edition cover: Genetics and treatmentOxidative stress and its relation to the pathophysiology of AMD and CNV (choroidal neovascularization—a common symptom of wet AMD)Polypoidal choroidal vasculopathy Microperimetry and psychophysical testing and ways to track geographic atrophy progression Non-VEGF pathways Retinal stem cells

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  • Age-Related Macular Degeneration
    Age-Related Macular Degeneration

    Age-Related Macular Degeneration (AMD) offers a consolidated view of a complex disorder by summarizing the latest evidence-based studies and translating their findings into practical, actionable knowledge.This concise resource covers the fundamentals of AMD diagnosis and treatment.It operates under a modern definition of AMD which acknowledges the range of presentations that ophthalmologists see in practice.Offering practical, clinical guidance in addition to capturing new therapeutic approaches in the pipeline, this book is an essential reference for ophthalmologists, optometrists, and researchers. . Takes a concise yet comprehensive approach to AMD, covering both basic science and clinical guidance. . Features clinical guidelines on the diagnosis and treatment of AMD, including classification, signs/symptoms, imaging, and differential diagnosis in the pre-optical coherence tomography (OCT) and modern OCT eras. . Presents up-to-date information on AMD therapies currently in the development pipeline and offers insights for the future of translational research. . Explains molecular genetics and pathogenic events of AMD from both basic and clinical perspectives, which may help readers seek promising new therapeutic targets .Contains more than 112 full-color illustrations with multimodal imaging techniques that clearly demonstrate AMD pathophysiology and clinical pathology.

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  • Scour Manual : Current-Related Erosion
    Scour Manual : Current-Related Erosion

    Ever since the publication in 1997 the original Scour Manual has helped many practising hydraulic engineers to deal with scour processes near hydraulic structures.In recent years new insights, such as probabilistic calculations, offered new opportunities to design structures more economically.These new insights are included in this update of the original Scour Manual, which is focussing entirely on current-related scour.This manual provides the engineer with useful practical methods to calculate the dimensions of scour holes in the pre-feasibility and preliminary stages of a project, and gives an introduction to the most relevant literature.This updated Scour Manual contains guidelines that can be used to solve problems related to scour in engineering practice and also reflects the main results of all research projects in the Netherlands in recent decades.The so-called Breusers equilibrium method has a central role, which can basically be applied to all situations where local scour is expected.The method allows to predict the scour depth as a function of time, provided that the available knowledge about scour at the specific structure is sufficient.For structures with insufficient knowledge available, alternative scour prediction rules are presented.The treatment of local scour is classified according to the different types of structures.Each type of structure is necessarily schematised to a simple, basic layout.The main parameters of a structure and the main parts of the flow pattern near a structure are described briefly insofar they are relevant to the description of scour phenomena.New scour formulas for the equilibrium scour have been elucidated.Evaluating a balance of forces for a control volume, it is possible to develop scour equations for different types of flow fields and structures, i.e. jets, abutments and bridge piers. As many scour problems are still not fully understood, attention is paid to the validity ranges and limitations of the formulas, as well as to the accuracy of the scour predictions.This information can also be used to carry out a risk assessment using a safety philosophy based on a probabilistic analysis or an approach with a safety factor.Moreover, the information on the strength of soils is extended and aspects are addressed such as scour due to shear failures or flow slides, that can progressively damage the bed protection which might lead to the failure of hydraulic structures. This updated Scour Manual presents scour prediction methods and deals with practically related scour problems.Consultants and contractors were invited to provide case studies of realized projects, including the methods that were followed.These case studies will help with grasping the concept of scour by the flow of water.This manual provides the engineer with the latest knowledge and with case studies that show how to apply the formulas and their limitations.

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  • Doctor Faustus : With Related Texts
    Doctor Faustus : With Related Texts

    This new edition of Christopher Marlowe’s Doctor Faustus offers the complete 1604 A-text with embedded selections from the 1616 B-text.Its innovative format will make it easier for readers to note differences between these texts and to consider what is gained and lost in viewing them both separately and together.A full Introduction to the play, notes, and a rich selection of related texts further enhance the value of this edition to students of Renaissance drama, Reformation theology, magic, and occult philosophy.

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  • Does anyone know a good gift related to manga?

    A good gift related to manga could be a set of manga books from a popular series or a gift card to a manga bookstore. Another idea could be to gift a subscription to a manga streaming service or a membership to a manga fan club. Additionally, merchandise such as posters, keychains, or clothing featuring characters from their favorite manga series could also make a great gift for a manga enthusiast.

  • How are good grades and a high IQ related?

    Good grades and a high IQ are often related because individuals with a high IQ tend to have better cognitive abilities, such as critical thinking, problem-solving, and memory retention, which can help them excel academically. These individuals may grasp concepts more quickly, perform well on exams, and demonstrate a deeper understanding of the material, leading to higher grades. However, it is important to note that good grades can also be influenced by factors such as motivation, study habits, and time management skills, which may not necessarily be directly related to IQ.

  • Can you think of any good horse-related questions?

    Some good horse-related questions could be: - What are the different types of horse breeds and what are their characteristics? - How do you properly care for a horse, including feeding, grooming, and exercise? - What are some common health issues that horses may face and how can they be prevented or treated? - How are horses trained for different disciplines such as dressage, jumping, or racing? - What role have horses played in history and how are they still important in modern society?

  • What are some good horse-related channels on YouTube?

    Some good horse-related channels on YouTube include "YourRidingSuccess" which offers training tips and techniques for riders, "Evention TV" which provides educational videos on horse care and training, and "EquestrianCoach" which features instructional videos from top equestrian coaches. These channels offer a wealth of knowledge for both beginner and experienced riders looking to improve their skills and understanding of horses.

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