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  • Coronavirus Replication and Reverse Genetics
    Coronavirus Replication and Reverse Genetics

    Human coronaviruses caused the SARS epidemic that infected more than 8000 people, killing about ten percent of them in 32 countries.This book provides essential information on these viruses and the development of vaccines to control coronavirus infections.

    Price: 183.50 £ | Shipping*: 0.00 £
  • Time Series Econometrics : Learning Through Replication
    Time Series Econometrics : Learning Through Replication

    In this book, the author rejects the theorem-proof approach as much as possible, and emphasize the practical application of econometrics.They show with examples how to calculate and interpret the numerical results. This book begins with students estimating simple univariate models, in a step by step fashion, using the popular Stata software system.Students then test for stationarity, while replicating the actual results from hugely influential papers such as those by Granger and Newbold, and Nelson and Plosser.Readers will learn about structural breaks by replicating papers by Perron, and Zivot and Andrews.They  then turn to models of conditional volatility, replicating papers by Bollerslev.Finally, students estimate multi-equation models such as vector autoregressions and vector error-correction mechanisms, replicating the results in influential papers by Sims and Granger. The book contains many worked-out examples, and many data-driven exercises.While intended primarily for graduate students and advanced undergraduates, practitioners will also find the book useful.

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  • Pseudo-Authenticity and Tourism : Preservation, Miniaturization, and Replication
    Pseudo-Authenticity and Tourism : Preservation, Miniaturization, and Replication

    This book explores the concept of authenticity in tourism through the analysis of six tourist sites in Guangdong Province and Macau, China.Through a review of tourism literature, it develops the concept of pseudo-authenticity in which tourist sites and cultural products function to give signs of authenticity for tourists.This is achieved through the influence of media, authentic fakery, and façadism.Readers will gain greater insight into tourist sites in China that operate through cultural preservation, the miniaturization of cultural assets, and the replication of foreign signs through reproductions of foreign cities.The authors outline the tourist sites, an aesthetic analysis, on-site interviews with tourists, and an examination of online reviews of the sites. This is a useful work for scholars and students of tourism studies in China and around the world, especially those concerned with issues of authenticity and the effects of commodification on cultural assets.

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  • False Feedback in Economics : The Case for Replication
    False Feedback in Economics : The Case for Replication

    This book investigates why economics makes less visible progress over time than scientific fields with a strong practical component, where interactions with physical technologies play a key role.The thesis of the book is that the main impediment to progress in economics is "false feedback", which it defines as the false result of an empirical study, such as empirical evidence produced by a statistical model that violates some of its assumptions.In contrast to scientific fields that work with physical technologies, false feedback is hard to recognize in economics.Economists thus have difficulties knowing where they stand in their inquiries, and false feedback will regularly lead them in the wrong directions. The book searches for the reasons behind the emergence of false feedback.It thereby contributes to a wider discussion in the field of metascience about the practices of researchers when pursuing their daily business.The book thus offers a case study of metascience for the field of empirical economics. The main strength of the book are the numerous smaller insights it provides throughout.The book delves into deep discussions of various theoretical issues, which it illustrates by many applied examples and a wide array of references, especially to philosophy of science.The book puts flesh on complicated and often abstract subjects, particularly when it comes to controversial topics such as p-hacking. The reader gains an understanding of the main challenges present in empirical economic research and also the possible solutions.The main audience of the book are all applied researchers working with data and, in particular, those who have found certain aspects of their research practice problematic.

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  • What is the replication origin in DNA replication?

    The replication origin is a specific sequence of DNA where the process of DNA replication begins. It is the site where the two strands of the DNA double helix are separated and the replication machinery is assembled. The replication origin is recognized by specific proteins that initiate the unwinding of the DNA and the synthesis of new DNA strands. Each DNA molecule has multiple replication origins to ensure that the entire genome is replicated efficiently.

  • What is DNA replication?

    DNA replication is the process by which a cell makes an identical copy of its DNA. This process is essential for cell division and the transmission of genetic information from one generation to the next. It involves the unwinding of the DNA double helix, the synthesis of new complementary strands using the existing strands as templates, and the proofreading and correction of any errors. DNA replication ensures that each new cell receives a complete and accurate set of genetic instructions.

  • What is semiconservative replication?

    Semiconservative replication is the process by which DNA is copied during cell division. In this process, the two strands of the DNA double helix separate, and each strand serves as a template for the synthesis of a new complementary strand. As a result, each new DNA molecule contains one original strand and one newly synthesized strand. This ensures that the genetic information is preserved and passed on to the next generation of cells. This process was first proposed by James Watson and Francis Crick in 1953.

  • How does DNA replication occur?

    DNA replication occurs in a semi-conservative manner, where the two strands of the double helix are separated and each strand serves as a template for the synthesis of a new complementary strand. The enzyme helicase unwinds the double helix, creating two single strands. DNA polymerase then adds new nucleotides to each single strand, following the base-pairing rules (A with T, and C with G). This results in two identical double-stranded DNA molecules, each containing one original strand and one newly synthesized strand.

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  • Matters of Significance : Replication, Translation and Academic Freedom in Developmental Science
    Matters of Significance : Replication, Translation and Academic Freedom in Developmental Science


    Price: 25.00 £ | Shipping*: 3.99 £
  • A Student's Guide to Open Science: Using the Replication Crisis to Reform Psychology
    A Student's Guide to Open Science: Using the Replication Crisis to Reform Psychology

    ''[A] masterpiece from start to finish [...] It’s rare that what is essentially an instructive academic book is such a page turner.Pennington breathes life into what may have been a dry, procedural topic and peppers the scientific detail with entertaining anecdotes and activities.''The Psychologist“Dr Charlotte R.Pennington has pulled off a remarkable trifecta of being clear, concise, and comprehensive in covering the origins of the open science movement and practical advice for adopting the behaviors.”Professor Brian Nosek, Executive Director, Center for Open Science; University of Virginia, US''I believe this book will be extremely valuable to both students and academics who wish to further their understanding of transparent research in psychology, and I have already taken steps towards adding this as a core text in my department!'' Psychology Teaching Review“My hope is that every psychology student will finish their degree with a heavily annotated, well-thumbed copy of this important and timely book!”Dr Madeleine Pownall, University of Leeds, UK“This book should be on the reading list for all university science degrees and on all library bookshelves.It is concise, accessible, and remarkably interactive, with brilliant use of examples and learning activities.Is there a better instruction manual on how to do science properly?If there is, I haven’t seen it.”Professor Chris Chambers, Cardiff University, UK“This book will equip future generations with the tools necessary to improve our disciplines, and thereby represents a significant ray of hope for the future.Essential and timely.”Dr Emma Henderson, University of Surrey, UK A Student’s Guide to Open Science explores the so-called “replication crisis” in psychology (the inherent difficulties in replicating or reproducing research results to test the robustness of findings) while delving into the ways that open science can address the crisis by transforming research practice. Students will develop a fundamental understanding of the origins and drivers of the crisis and learn how open science practices can enhance research transparency, replication, and reproducibility. With a handy, digestible guide for students and researchers alike on how to implement open science practices within their own workflow, as well as pedagogic teaching and learning activities that can be re-used by educators, Pennington’s new book is an essential guide to navigating the replication crisis. Key features of this book include:• An overview of landmark events that will mark the history of the replication crisis. • Case studies of classic psychological studies undergoing replication. • Test yourself activities to reinforce learning of key concepts, including an open science crossword!• Top tips for adopting open science practices, including study preregistration, Registered Reports, and open materials, code, and data. • Useful illustrations to aid understanding and facilitate revision.New concepts and practices can often feel overwhelming, but this book aims to help students and educators pick what they want from the ‘open science buffet’ and return to the table to fill up their plates again and again.Remember, we are all students of open science and will be for many years to come!Dr Charlotte R.Pennington is a Lecturer in Psychology at Aston University, Birmingham, UK and a Fellow of the Higher Education Academy.She is an expert in open science and advocates for the teaching of this within higher education pedagogy.

    Price: 19.99 £ | Shipping*: 3.99 £
  • Good News, Bad News
    Good News, Bad News


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  • All News Is Good News
    All News Is Good News


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  • What is RNA self-replication?

    RNA self-replication is a process where RNA molecules are able to catalyze their own replication without the need for external enzymes. This ability is crucial for the early evolution of life on Earth, as it is believed to be a key step in the transition from prebiotic chemistry to the emergence of life. RNA self-replication involves the RNA molecule acting as both a template and an enzyme, allowing it to make copies of itself. This process is a fundamental aspect of the RNA world hypothesis, which suggests that RNA played a central role in the origin of life.

  • Where does DNA replication occur?

    DNA replication occurs in the nucleus of eukaryotic cells and in the cytoplasm of prokaryotic cells. In eukaryotic cells, DNA replication takes place during the S phase of the cell cycle, when the DNA is duplicated to ensure that each daughter cell receives a complete set of genetic information. The process involves the unwinding of the DNA double helix, the synthesis of new DNA strands using existing strands as templates, and the proofreading and correction of errors. Overall, DNA replication is a fundamental process that ensures the accurate transmission of genetic information from one generation to the next.

  • What is a replication bubble?

    A replication bubble is a region of DNA where the double helix has been unwound and separated to allow for DNA replication to occur. It is formed by the action of helicase enzymes that unwind the DNA strands, creating two single-stranded templates for the replication process. The replication bubble expands as the replication machinery moves along the DNA, synthesizing new strands of DNA. Replication bubbles are a key feature of DNA replication and allow for the efficient and accurate copying of genetic information.

  • What is the direction of replication?

    The direction of replication is bidirectional, meaning that it occurs in both directions simultaneously. This means that DNA replication proceeds in two opposite directions from the origin of replication. As the replication fork opens up, new DNA strands are synthesized in both directions by DNA polymerase enzymes. This bidirectional replication allows for the efficient and rapid duplication of the entire DNA molecule.

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